Twinnie's
If you find yourself near Duke University, Twinnie’s Cafe is an essential stop on your culinary journey. Nestled at 101 Science Dr, Durham, NC, this charming cafe has become a beloved staple for students and locals alike. With its warm ambiance and welcoming staff, Twinnie’s strikes the perfect balance between a casual eatery and a gourmet dining experience. You can reach them at +1 919-660-3944.
At Twinnie’s, the menu is an enticing parade of cafe-style dishes, ensuring that every visit offers something unique to savor. Guests rave about the chicken focaccia, a standout that has captured the hearts and taste buds of many, while the daily specials are crafted with care, showcasing seasonal ingredients and flavors that never disappoint. Whether you’re in the mood for a comforting panini or a refreshing caffeinated beverage, Twinnie’s caters to all cravings with a mix of hearty entrées and delightful drinks. The vibrant drink menu complements their food perfectly, making it easy to find something exciting to wash down your meal.
The atmosphere is invigorating yet relaxed, inviting you to sit back and enjoy your meal. Indoor seating offers a respite from the bustling campus atmosphere, while al fresco options provide a stunning view of the verdant Duke Campus. As noted by Bryan Howell, it’s a wonderful locale to catch up with friends or colleagues over a delicious lunch infused with local charm.
What truly sets Twinnie’s apart, though, is its incredible team. Customers often highlight the exceptional service provided by Jack and his crew, who not only know how to prepare a mean sandwich but also create a friendly, engaging environment. Natalie Chen’s review encapsulates this perfectly, as she mentions the joy of weekly visits and Jack’s fantastic recommendations that make each trip feel special. This kind of interaction transforms a simple cafe visit into an experience where customers feel valued and welcomed.
Additionally, Twinnie’s has garnered acclaim for its selection of desserts, making it an excellent spot for those looking to indulge their sweet tooth after a savory meal. Just as Shelley Willis Queen discovered, the creativity in the kitchen can lead to some unforgettable culinary delights, like the chicken cordon bleu with pottanesca sauce that had her raving about her experience.
For anyone exploring Durham, Twinnie’s Cafe promises more than just a meal—it offers a taste of the local community, genuine hospitality, and a sense of belonging. Don’t miss out on the chance to be part of this vibrant gathering spot; stop by Twinnie’s for a quick bite or linger longer and enjoy the unique offerings that keep loyal customers returning week after week.
90 Reviews
06 Sep 2025
26 Aug 2025
27 Jun 2025
14 Jun 2025
13 Jun 2025
05 Jun 2025

Tim Hortons Blvd. Tamaulipas

Cafeteria & Bar La Plaza(admin Loterias)

Brundon Lane Cafe
Join the Twinnie's Newsletter
Get the latest updates on seasonal pastries, special events, and local highlights directly in your inbox.